منابع مشابه
Cancer chemoprevention by carotenoids.
Carotenoids are natural fat-soluble pigments that provide bright coloration to plants and animals. Dietary intake of carotenoids is inversely associated with the risk of a variety of cancers in different tissues. Preclinical studies have shown that some carotenoids have potent antitumor effects both in vitro and in vivo, suggesting potential preventive and/or therapeutic roles for the compounds...
متن کاملCarotenoids in cancer chemoprevention and therapeutic interventions.
Carotenoid (CARs: beta-carotene BC and/or canthaxanthin CX) supplementation have been shown to be chemopreventive in animals, since 1980, against direct or indirect chemical carcinogenesis/photo-carcinogenesis of the skin, breast, stomach, salivary glands, colon-rectum, urinary bladder, and against transplanted tumors. This action could be either independent of or dependent on pro-vitamin A act...
متن کاملThe chemoprevention of cancer by dietary carotenoids: studies in mouse and human cells
Dietary carotenoids, particularly beta-carotene, have in many epidemiologic studies been associated with a decreased risk of cancer. Experimental studies have been inhibited by difficulties in delivering these molecules to target cells. A novel delivery system has been developed in the mouse 10T1/2 cell line. With these cells several carotenoids of dietary and commercial interest have been show...
متن کاملCancer prevention by carotenoids.
Various natural carotenoids seem to be valuable for cancer prevention, and these carotenoids may be more suitable in combinational use, rather than in single use. In fact, we have proven that combinational use of natural carotenoids resulted in significant suppression of liver cancer. Patients of viral hepatitis with cirrhosis were administered with beta-cryptoxanthin-enriched Mandarin orange j...
متن کاملCancer chemoprevention. Part 1: Retinoids and carotenoids and other classic antioxidants.
Cancer chemoprevention is the use of specific natural or synthetic substances with the objective of reversing, suppressing, or preventing carcinogenic progression to invasive cancer. Currently, numerous chemopreventive agents are in various stages of development and testing. Part 1 of this two-part series provides an overview of issues unique to chemoprevention trials, including the use of surr...
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ژورنال
عنوان ژورنال: Molecules
سال: 2012
ISSN: 1420-3049
DOI: 10.3390/molecules17033202